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Sold Globally Since 2008

The Ultimate Standard
in Wellness

What if you could strengthen your immune system naturally exactly the way nature intended, to maintain superior health and live life to the fullest by the power within your cells?

Immune Formulation 200® is a dietary supplement and glutathione precursor, a true scientific breakthrough and a remarkable revelation in modern science, discovered by Dr. Albert B. Crum, M.D., DSc (Hon), M.S., a graduate of Harvard Medical School. It helps the body respond to inflammation, expel toxins, and manage oxidative stress naturally within every cell, exactly as nature designed, supporting a strong immune system and promoting cellular health.*

Clinically Formulated
All Natural
Made in the USA
ProImmune Immune Formulation 200 Jar

As Seen In & Trusted By

ProImmune
Where nature restores health all naturally

Backed by Science - Protected by Our Guarantee

“We stand behind the quality and effectiveness of our formula with complete confidence. Try it for 60 days. If you're not satisfied with your results or improvements to your health, we'll refund your purchase no questions asked. Because when something truly works, it should speak for itself. Recommended by physicians, pharmacies and health centers across America.”

— Joseph V Cassarino

Dedicated to improving your health

A New Era in Natural Health

A new era in health is emerging focused on improving wellness all naturally by working in harmony with the body’s cellular processes. At the center of this approach is intracellular glutathione synthesis, a fundamental biological process essential for immune function.

Glutathione production dates back about 3.5 billion years, when early cells first developed the ability to create it internally. Since then, glutathione has remained vital, acting as the body’s primary antioxidant and key detoxification system within every cell.

Historically, the body produced enough glutathione to manage toxins and oxidative stress. However, since the Industrial Revolution, increased exposure to environmental toxins has challenged this ability, contributing to higher levels of oxidative stress and inflammation.

ProImmune is designed to support intracellular glutathione synthesis through an all-natural formulation. Unlike traditional supplements or delivery methods, such as NAC, liposomal, or IV glutathione which bypass natural pathways, ProImmune works in alignment with the body’s own biochemical processes like a lock and key. At the cellular level, glutathione synthesis relies on precise, substrate-specific enzymes directly inside cells, functioning like a “lock and key.” ProImmune supports this mechanism by providing the exact building blocks the body naturally recognizes and uses, rather than bypassing it.

ProImmune contains the three necessary amino acids required for glutathione production, along with selenium, a critical cofactor that enhances this process. This approach supports effective and efficient, sustained intracellular production in a way that synthetic or externally delivered glutathione cannot fully replicate.

This reflects a shift toward supporting the body’s innate systems rather than overriding them, leveraging mechanisms established by nature long before modern medicine.

Many individuals using ProImmune report improvements in overall health and well-being, including positive changes in chronic conditions. This is what sets ProImmune apart from any other synthetic glutathione molecule or product on the market.

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Another Important Message from Joe Cassarino

The Benefits of ProImmune®

Joseph V Cassarino, Founder of TheBestImmuneSupport.com, describes the health benefits of ProImmune® Immune Formulation 200®

Master The Art of Perfect Health With The Scientific Revelation of ProImmune

Groundbreaking Advanced Immune Support

Scientific Discovery

Formulated by Dr. Albert B. Crum, M.D., DSc (Hon), M.S., Harvard Medical School Graduate. A groundbreaking discovery utilizing ultra-fine minute particle sizes that restores glutathione levels directly within your cells.

Physician Recognized

Recognized nationwide by physicians, pharmacies, and health professionals as the most effective and efficient intracellular glutathione synthesis delivery system on earth following precise principles of evolution and nature. ProImmune is compared to Planck's theory (h) — always has been and will always be a universal constant.

Since 2008

Trusted by thousands worldwide for over 15 years, delivering cellular restoration directly at its source.

Cellular health is the foundation everything else is built on

The Master Antioxidant

Glutathione is often called the body's "master antioxidant" — essential for immune function, detoxification, and cellular health.

01

Immune Defense

Supports and strengthens the body's natural immune response at the cellular level.

02

Cellular Detox

Helps the body eliminate toxins and free radicals that damage cells over time.

03

Energy & Vitality

Optimal glutathione levels are linked to increased energy and reduced fatigue.

04

Healthy Inflammation

Helps the body manage healthy inflammation response for overall wellness.

05

Anti-Aging

Protects cells from oxidative stress, a key driver of premature aging.

06

Brain Health

Supports cognitive function and helps protect neural pathways from oxidative damage.

Optimal health begins by maintaining ample intracellular glutathione levels, something that isn’t taught in medical schools but is factual

Choose Your Plan

One-Time
$75/jar
  • 60+ servings per jar
  • Free US shipping
  • All-natural formula
Buy Now
Bulk Order (6 Jars)
$63.75/jar
Save 15% — Best value
  • 6-month supply
  • Free US shipping
  • All-natural formula
Buy 6 Jars

Wholesale buyers: enter your promotional code at checkout for wholesale pricing.
New Practitioners call Joseph at 845-206-8104 to receive a code.

Science for Physician’s and Pharmacies

The Secrets For Optimal Health Are Already Inside You, Unlock Them With ProImmune

How ProImmune Works

Immune Formulation 200® is a glutathione precursor which allows each cell in the body to manufacture its own glutathione.* University researched with an $88M National Institutes of Health grant, ProImmune activates the Nrf2 Gene which supports immune functions.*

This intracellular approach means your body produces glutathione naturally, directly within the cell — exactly as nature intended.

15+
Years on Market
200+
Healthcare Providers
40
Global Patents
Read the Research
Glutathione Synthesis Chart by Dr. Albert B. Crum

Click chart to view full size

Those Who Take ProImmune Don't Just Survive, They Thrive

Real stories by real people

"ProImmune may be the single most important supplement to have in your arsenal."

J
Jeffrey I. Barke, MD
Board Certified Primary Care Physician • Newport Beach, CA

"We love ProImmune and have been using it for years! When my son suffered his brain injury, we started ProImmune right away. I truly believe this product preserved my son's cognitive function. We continue to use ProImmune daily, and he has had zero hospitalizations due to illnesses!"

A
Amy & Kevin Oates
North Richland Hills, TX

"Concerning the MTHFR mutation alone, approximately 30-60% of the population is glutathione deficient. ProImmune is a very effective way to boost glutathione levels and it allows the body to convert to glutathione more efficiently than NAC."

C
Dr. Carey Wennerstrom
McDonagh Medical Center • Gladstone, MO

"ProImmune Everyday, I get it done with ProImmune every single day! All athletes should be taking two scoops of ProImmune a day, once in the AM and PM."

R
Ricky Simon
UFC Fighter

"We recommend and sell ProImmune - Immune Formation 200 in our pediatric center because ProImmune boosts glutathione levels better than NAC. Additionally, it is a semi-sweet tasting powder that children like or it can be added to food being cooked since it is heat-stable."

J
Dr. Joseph Malak, MD
Founder, Bambini Pediatrics • Hudson Valley, NY

"As a Psychologist Consultant specializing in serious mental conditions across America, I recommend ProImmune to the majority of my patients because I find it effectively supports neurological and psychological conditions plus reduces anxiety, depression and more - ProImmune is an all natural remedy every clinician should be recommending to patients and every person should be taking."

K
Dr. Karla Von Ehrenkrook
DD, PhD, DCh • Phoenix, AZ

"I started using ProImmune about three weeks ago and I love it! As someone who has battled tick born illnesses for the past 10 years, it’s an even bigger challenge to keep my immune system strong. I have to say that ProImmune has been a life saver for me. People should pay attention. ProImmune really works!!"

J
Jade Platania
Rhinebeck, NY

"ProImmune may be the most important supplement available! I use this daily and recommend to all my patients!"

J
Dr. Judy Mikovits
PhD Molecular Biology & Biochemist
Newport Beach, CA — TheRealDrJudy.com

"ProImmune is an all-natural, pharmaceutical-grade product utilized to synthesize directly inside cells. ProImmune offers the absolute most effective form of bioavailability in existence."

F
Dr. Edward (Ted) Fogarty, MD
Received Federal Cares Act Approval for ProImmune as the only all-natural Covid Countermeasure in 2020 when vaccines received the same approval

Protect today what you'll depend on tomorrow

Frequently Asked Questions

Immune Formulation 200® is a dietary supplement and glutathione precursor, created intracellularly for super effective and efficient bodily production of glutathione, The Master Antioxidant.* It was university researched with an $88M National Institutes of Health grant and activates the Nrf2 Gene which supports immune functions.* It is safe, all natural to the body and produced inside the cells as nature intended.*

Most glutathione supplements deliver pre-formed glutathione that gets broken down in digestion. ProImmune's patented formula works intracellularly, giving your body what it needs to produce glutathione on its own — right where it's needed most.

Yes! Shipping is free within the Continental United States. Please allow 7–10 days for delivery. For international orders, please call Willner Chemists at 212-682-2817.

Absolutely. You can cancel your monthly or bimonthly subscription at any time with no penalties or fees.

Suggested Use: One level scoop twice a day consistently for seniors and anyone seeking to strengthen their immune system all naturally to shield from winter colds and other symptoms. (AM and PM). Age 6 to 12: one (1) level scoop (1.6g) per day. Under age 6: consult your physician. Take orally or add to food or beverage and swallow after it dissolves on the tongue. The semi-sweet tasting powder has no sugar, calories, carbohydrates or artificial sweeteners. Keto-friendly. One jar contains more than 60 servings and can last one to two months per adult.

Satisfaction guaranteed or your money back! If for any reason you are not completely satisfied, please email info@TheBestImmuneSupport.com for instructions on where to mail your jar and we will issue a full refund upon receiving your unopened jar within 60 days. Excludes shipping fees.

Yes, we offer wholesale pricing for qualified buyers. Please visit our wholesale page or contact us for your promotional code.

Once your order is placed, you will receive a confirmation email. When your order ships, you will receive a second email with shipping details and a tracking number, so you can check on your order. Please remember to check your spam or junk email folder for these notifications.

Orders placed by 12:00pm are typically shipped the same day and typically arrive within 5 business days. Due to delays with the U.S. Postal Service, sometimes delivery may take 7 to 10 business days.

There are approximately 62 scoops per jar, and that number is based on filling the scooper a little below the rim. If you fill the scoop above the rim, you will have fewer scoops per jar.

For ages 6 to 12, one level scoop (1.6g) per day is suggested. For children under age 6, please consult your physician before use.

ProImmune has a semi-sweet taste with no sugar, calories, carbohydrates or artificial sweeteners. It is keto-friendly. You can take it orally, let it dissolve on your tongue, or add it to food or any beverage.

Glutathione is often called “The Master Antioxidant.” It is the body’s most powerful natural defense molecule, playing a critical role in immune function, detoxification, and cellular protection. Every cell in the body depends on glutathione to neutralize free radicals and remove toxins.*

You can order directly from this website, or find ProImmune on Amazon and Walmart. ProImmune is also available at select health food stores and pharmacies across the country. Visit our Store Locations page for details. For international orders, call Willner Chemists at 212-682-2817.

Nature gave your body the blueprint ~ Give it the right tools and nutrients to thrive, give it ProImmune

Joseph V Cassarino - Founder, Best Immune Support

Joseph V Cassarino

Founder, Best Immune Support — Boca Raton, FL

"May you live every day in your best health possible!"

As the authorized global distributor for Dr. Albert B. Crum, M.D., DSc (Hon), M.S., and ProImmune Co. LLC, Best Immune Support is dedicated to bringing this groundbreaking supplement to people worldwide. Joseph was hand selected by Dr. Albert B. Crum to introduce ProImmune® - Immune Formulation 200® to the public, medical providers, and health food markets across the globe.

The Doctor Fogarty Show - News & Talk - Sunday 7:30 AM - 99.9 WXJB FM

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The Dr. Fogarty Show featuring guest speaker Joseph V Cassarino

Find Us Near You

ProImmune is available at pharmacies and health centers across America.

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Improving the immune system is the secret to improving health

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ProImmune ~ Positively impacting lives across America since 2008

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* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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